FITC标记的乙酰基转移酶10抗体
产品名称： FITC标记的乙酰基转移酶10抗体
英文名称： Anti-NAT10/FITC
产品编号： HZ-7757R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-NAT10/FITC Conjugated antibody
FITC标记的乙酰基转移酶10抗体
| 英文名称 | Anti-NAT10/FITC |
| 中文名称 | FITC标记的乙酰基转移酶10抗体 |
| 别 名 | ALP; hALP; KIAA1709; N acetyltransferase 10; N acetyltransferase 10 GCN5 related; N acetyltransferase like; N acetyltransferase like protein; N-acetyltransferase 10; NAT10; NAT10_HUMAN; NET43. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞分化 细胞骨架 细胞外基质 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 116kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NAT10 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division. Function: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division. Subunit: Interacts with SUN1 (via N-terminus). Also interacts with TERT. Subcellular Location: Nucleus, nucleolus. Note=Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase. Similarity: Belongs to the UPF0202 family. Contains 1 N-acetyltransferase domain. Database links: UniProtKB/Swiss-Prot: Q9H0A0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
具有蛋白乙酰转移酶活性。可以同时乙酰化组蛋白和微管。Histone乙酰化可调节转录和有丝分裂染色体的解聚。通过刺激TERT的转录激活端粒酶活性，也可能通过影响端粒酶亚单位的组装、分解和定位平衡来调节端粒酶的功能。乙酰化α-微管蛋白，可能影响微管的稳定性和细胞分裂。