AD7C-NTP,神经丝蛋白抗体

产品编号HZ-0720M
英文名称AD7C-NTP
中文名称神经丝蛋白抗体
别 名neuronal thread protein AD7c-NTP; AD7c-NTP.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域免疫学 神经生物学
抗体来源Mouse
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
AD7C-NTP,神经丝蛋白抗体分 子 量41kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human AD7C-NTP
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
AD7C-NTP,神经丝蛋白抗体PubMedPubMed
产品介绍background:
This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease.

Database links:
GenBank: AAC08737.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

AD7C-NTP,神经丝蛋白抗体AD7C-NTP是存在于神经元中的一种41Kda的蛋白质，在AD患者脑内选择性升高，和其病理过程相关，AD7C-NTP基因也只在神经元表达，AD患者脑脊液中AD7C-NTP表达升高， AD7C-NTP作为AD早期诊断和确诊的生物化学标志正引起越来越多的关注.

产品图片

Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-AD7C-NTP Polyclonal Antibody, Unconjugated(bs-0720M) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0024) and DAB(C-0010) staining Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-AD7C-NTP Polyclonal Antibody, Unconjugated(bs-0720M) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0024) and DAB(C-0010) staining