Recombinant Human IL-16 (130 a.a.)
产品名称： Recombinant Human IL-16 (130 a.a.)
英文名称： Recombinant Human IL-16 (130 a.a.)
产品编号： 200-16
产品价格： 0
产品产地： USA
品牌商标： PEPROTECH
更新时间： null
使用范围： null
上海研卉生物科技有限公司
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产品编号:
200-16
别名:
LCF (Lymphocyte Chemoattractant Factor)
描述:
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.5 kDa protein consisting of 130 amino acid residues.
氨基酸序列:
MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to chemoattract human CD4+ T lymphocytes using a concentration range of 1.0-100.0 ng/ml.
交叉反应:
Human + Mouse