FITC标记的核小体相关激酶HIPK1抗体
产品名称： FITC标记的核小体相关激酶HIPK1抗体
英文名称： Anti-HIPK1/FITC
产品编号： HZ-17403R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HIPK1/FITC Conjugated antibody
FITC标记的核小体相关激酶HIPK1抗体
| 英文名称 | Anti-HIPK1/FITC |
| 中文名称 | FITC标记的核小体相关激酶HIPK1抗体 |
| 别 名 | Hipk 1; Hipk1; HIPK1_HUMAN; Homeodomain interacting protein kinase 1; Homeodomain interacting protein kinase 1 like protein; Homeodomain-interacting protein kinase 1; Myak; Nbak 2; Nbak2; Nuclear body associated kinase 2; Nuclear body associated kinase 2b. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 激酶和磷酸酶 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Macaque Monkey |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 131kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HIPK1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [provided by RefSeq, Jul 2008] Function: May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation. Subcellular Location: Nucleus. Cytoplasm. Predominantly nuclear. Tissue Specificity: Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines. Post-translational modifications: Autophosphorylated. Phosphorylated and activated by JNK1. Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily. Contains 1 protein kinase domain. Database links: Entrez Gene: 204851 Human Entrez Gene: 15257 Mouse Entrez Gene: 365895 Rat Omim: 608003 Human SwissProt: Q86Z02 Human SwissProt: O88904 Mouse SwissProt: A4L9P5 Rat Unigene: 532363 Human Unigene: 20827 Mouse Unigene: 4151 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白属于蛋白激酶和HIPK亚家族的SE/THR家族。它磷酸化同源域转录因子，也可能作为同源域转录因子的共同抑制剂。选择性剪接结果编码四种转录变体，编码四种不同的亚型。[ RefSeq，JUL 2008 ]