重组人骨形态发生蛋白4（人BMP-4）
产品名称： 重组人骨形态发生蛋白4（人BMP-4）
英文名称： Recombinant Human Bone Morphogenetic Protein 4 (Human BMP-4)
产品编号： 92053ES10
产品价格： 1855.00
产品产地： 翌圣生物
品牌商标： Yeasen
更新时间： 2024-12-10T11:28:44
使用范围： null
| 规格 | 价格 |
| 20μg | 1855.0 |
| 100 μg | 7865.0 |
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Product Description
Bone morphogenetic protein-4 (BMP-4) is one of nine structurally related BMPs belonging to the transforming growth factor-beta (TGF-beta) superfamily of secreted proteins. The human BMP-4 shares 98 % sequence indentity with mouse BMP-4. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4, a stimulator of chondrogenesis, both in vitro and in vivo, is a potential therapeutic agent for cartilage regeneration.
Product Properties
Synonyms
BMP2B, BMP-2B, BMP2B1, BMP2BMCOPS6, BMP4,DVR4, MCOPS6, OFC11, ZYME
Accession
P12644
Source
E.coli-derived human BMP-4 protein, Ser293-Arg408, E399D.
Molecular Weight
The recombinant Human BMP4 predicts a molecular mass of 13.25 kDa.
Tag
None
Purity
> 95% by SDS-PAGE
Biological Activity
Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.08-0.4ug/mL.
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from sterile 30% Acetonitrile, 1/1000 TFA. Normally 5% - 8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Avoid repeated freeze-thaw cycles.
2.For your safety and health, please wear lab coats and disposable gloves for operation.
3.For research use only.
Ver. CN20230810