Anti-RGR Polyclonal Antibody
产品名称: Anti-RGR Polyclonal Antibody
英文名称: RP44
产品编号: K007139P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IHC
北京索莱宝科技有限公司--实验室产品
- 联系人 :
- 地址 : 北京市通州区马驹桥联东U谷景盛南四街85A三层
- 邮编 :
- 所在区域 : 北京
- 电话 : 010-563*1250 点击查看
- 传真 : 点击查看
- 邮箱 : 2748554845@qq.com
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.