DNASE2抗体-抗体-抗体-生物在线
DNASE2抗体

DNASE2抗体

商家询价

产品名称： DNASE2抗体

英文名称： DNASE2Antibody

产品编号： XY15934-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 DNASE2抗体

Applications
Tested Applications: ELISA, WB, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HeLa cells
Positive IP detected in HeLa cells
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
 DNASE2抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 15934-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 15934-1-AP(DNASE2 antibody) at dilution of 1:300
  • 15934-1-AP;HeLa cellsIP Result of anti-DNASE2 (IP:15934-1-AP, 4ug; Detection:15934-1-AP 1:300) with HeLa cells lysate 3200ug.
Product Information DNASE2抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: DNASE2 fusion protein ag8781 Full Name: Deoxyribonuclease II, lysosomal
Caculated Molecular
Weight:		 360aa,40 kDa Observed Molecular 
Weight:		 32 kDa
GenbankNo BC010419 GeneID: 1777
Symbol DNASE2 Synonyms Acid DNase, Deoxyribonuclease 2 alpha, Deoxyribonuclease II alpha, DNase II alpha, DNASE2, DNASE2A, DNL, DNL2, Lysosomal DNase II, R31240_2
Background

DNASE2, or 'acid DNase,' hydrolyzes DNA under acidic conditions and is one of 2 distinct mammalian DNases. It hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. It has a key role in the degradation of nuclear DNA in cellular apoptosis during development [PMID:18812394]. Besieds, it is necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. It has been demonstrated to be responsible forDNA degradation in apoptotic cells engulfed by macrophages and exogenous DNA on the skin surface [PMID:23019102]. DNASE2抗体

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