FGFBP2,纤维细胞生长因子结合蛋白2抗体

产品编号HZ-11284R
英文名称FGFBP2
中文名称纤维细胞生长因子结合蛋白2抗体
别 名KSP37; FGF-binding protein 2; FGF-BP2; FGFBP-2; FGFBP2; FGFP2_HUMAN; Fibroblast growth factor-binding protein 2; HBp17-related protein; HBp17-RP; Ksp37; 37 kDa killer-specific secretory protein.
说 明 书0.1ml 0.2ml
研究领域免疫学 信号转导 生长因子和激素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
FGFBP2,纤维细胞生长因子结合蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
细胞定位细胞外基质 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FGFBP2/KSP37
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FGFBP2,纤维细胞生长因子结合蛋白2抗体PubMedPubMed
产品介绍background:
KSP37 is a 223 amino acid protein that is secreted into the extracellular space and belongs to the fibroblast growth factor-binding protein family. Expressed in serum, as well as in cytotoxic T lymphocytes and peripheral leukocytes, KSP37 is thought to be involved in lymphocyte-mediated immunity, possibly playing a role in the development of asthma. The gene encoding KSP37 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Subcellular Location:
Secreted. extracellular space.

Tissue Specificity:
Expressed in serum, peripheral leukocytes and cytotoxic T lymphocytes, but not in granulocytes and monocytes (at protein level).

Similarity:
Belongs to the fibroblast growth factor-binding protein family.

Database links:
Entrez Gene: 83888 Human
Omim: 607713 Human
SwissProt: Q9BYJ0 Human
Unigene: 98785 Human

FGFBP2,纤维细胞生长因子结合蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-FGFBP2 Polyclonal Antibody, Unconjugated(HZ-R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining