磷酸化基质重塑相关蛋白PARVA抗体-抗体-抗体-生物在线
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磷酸化基质重塑相关蛋白PARVA抗体

磷酸化基质重塑相关蛋白PARVA抗体

商家询价

产品名称: 磷酸化基质重塑相关蛋白PARVA抗体

英文名称: phospho-Parvin alpha (Ser8)

产品编号: hz-19894R

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

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 Rabbit Anti-phospho-Parvin alpha (Ser8) antibody 

 

产品编号 hz-19894R
英文名称 phospho-Parvin alpha (Ser8)
中文名称 磷酸化基质重塑相关蛋白PARVA抗体
别    名 Parvin alpha (phospho S8); p-Parvin alpha (phospho S8); Actopaxin; Alpha parvin; Alpha-parvin; Calponin like integrin linked kinase binding protein; Calponin-like integrin-linked kinase-binding protein; CH ILKBP; CH-ILKBP; FLJ10793; FLJ12254; Matrix remodelling associated 2; Matrix remodelling associated protein 2; Matrix-remodeling-associated protein 2; MXRA 2; MXRA2; PARV A; PARVA; PARVA_HUMAN.  
   
产品类型 磷酸化抗体 
研究领域 细胞生物  信号转导  结合蛋白  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Parvin alpha around the phosphorylation site of Ser8:QK(p-S)PS 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Function:
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis.

Subcellular Location:
Cell junction > focal adhesion. Cell membrane. Cytoplasm > cytoskeleton. Constituent of focal adhesions.

Tissue Specificity:
Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.

Similarity:
Belongs to the parvin family.
Contains 2 CH (calponin-homology) domains.

Gene ID:
55742

Database links:

Entrez Gene: 55742 Human

Entrez Gene: 57342 Mouse

Entrez Gene: 57341 Rat

Omim: 608120 Human

SwissProt: Q9NVD7 Human

SwissProt: Q9EPC1 Mouse

SwissProt: Q9HB97 Rat

Unigene: 432914 Human

Unigene: 143763 Mouse

Unigene: 92564 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Sample: 
Embryo (Mouse) Lysate at 40 ug
Primary: Anti-phospho-Parvin alpha (Ser8) (bs-19894R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD