FITC标记的皮质醇结合球蛋白抗体
产品名称： FITC标记的皮质醇结合球蛋白抗体
英文名称： Anti-ERPINA6/Cortisol Binding Globulin/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ERPINA6/Cortisol Binding Globulin/FITC Conjugated antibody
FITC标记的皮质醇结合球蛋白抗体
| 英文名称 | Anti-ERPINA6/Cortisol Binding Globulin/FITC |
| 中文名称 | FITC标记的皮质醇结合球蛋白抗体 |
| 别 名 | CBG; CBG_HUMAN; corticosteroid binding globulin; Corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; serpin A6; serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; SERPINA6; transcortin. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 转运蛋白 结合蛋白 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cortisol Binding Globulin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008] Function: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Subcellular Location: Secreted. Tissue Specificity: Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. Post-translational modifications: N-glycosylated; binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. DISEASE: Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. Similarity: Belongs to the serpin family. Database links: Entrez Gene: 866 Human Omim: 122500 Human SwissProt: P08185 Human Unigene: 532635 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一种具有皮质类固醇结合特性的α球蛋白。这是大多数脊椎动物血液中糖皮质的主要转运蛋白。该基因定位于包含几个紧密相关的丝氨酸蛋白酶抑制剂的染色体区域，这些抑制剂可能是通过复制事件进化而来的。[ RefSeq，JUL 2008 ]