FITC标记的富含亮氨酸跨膜纤连蛋白1抗体
产品名称： FITC标记的富含亮氨酸跨膜纤连蛋白1抗体
英文名称： Anti-FLRT1/FITC
产品编号： HZ-12361R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FLRT1/FITC Conjugated antibody
FITC标记的富含亮氨酸跨膜纤连蛋白1抗体
| 英文名称 | Anti-FLRT1/FITC |
| 中文名称 | FITC标记的富含亮氨酸跨膜纤连蛋白1抗体 |
| 别 名 | Fibronectin-like domain containing leucine rich transmembrane protein 1; Fibronectin-like domain-containing leucine-rich transmembrane protein 1; FLRT1; FLRT1_HUMAN; Leucine rich repeat transmembrane protein FLRT1; Leucine-rich repeat transmembrane protein FLRT1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 信号转导 细胞粘附分子 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 69kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FLRT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. FLRT1 (fibronectin leucine rich transmembrane protein 1) is a 646 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten LRR repeats. Expressed in kidney and brain, FLRT1 is thought to play a role in cell adhesion and receptor signaling. FLRT1 shares similarity with FLRT2 and FLRT3 and is subject to post-translational N-glycosylation. The gene encoding FLRT1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Function: May have a function in cell adhesion and/or receptor signaling. Subcellular Location: Membrane. Tissue Specificity: Expressed in kidney and brain. Post-translational modifications: N-glycosylated. Similarity: Contains 1 fibronectin type-III domain. Contains 10 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: UniProtKB/Swiss-Prot: Q9NZU1.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
富含亮氨酸（LRR）的重复序列是20-30个氨基酸基序，形成疏水的_/马蹄形折叠，允许其在紧密包装的核心内容纳几个亮氨酸残基。所有LRR重复序列都包含一个可变片段和一个高度保守的片段，后者占整个LRR基序的11或12个残基。FLRT1（富含纤维连接蛋白亮氨酸的跨膜蛋白1）是一种646个氨基酸的单程I型膜蛋白，含有一个纤维连接蛋白III结构域和10个LRR重复序列。在肾脏和脑中表达，FLTR1被认为在细胞粘附和受体信号传导中起作用。FLTR1与FLTR2和FLTR3相似，并受翻译后N-糖基化的影响。编码FLTR1的基因映射到人类11号染色体，该基因含有1400个以上的基因，并包含人类基因组的近4%。