Pan anti-acetyllysine antibody
agarose conjugated beads (Premium)    Cat#PTM-104 
Pack    Size:0.5mL               Price: ￥11800.00 

            

                

                    

                        

                            
                        
                    
                
            
        




























Product Description: A mixture of high quality rabbit-derived polyclonal and mouse-derived monoclonal anti-acetyllysine antibodies are cross-linked to beaded agarose with stable amide linkages. With the combined advantages of polyclonal and monoclonal antibodies in global proteomic screening of lysine acetylation, this product presents extraordinary capability to specifically capture the peptides/proteins bearing lysine acetylated residues. 
Formulation: 0.5 mL of drained agarose in 1 mL of 50% glycerol slurry.

Specificity: With the immobilization of highly specific anti-acetyllysine antibody, the acetyllysine antibody beaded agarose selectively captures peptides/proteins bearing acetyllysine residues, but does not cross-react with the peptides/proteins bearing structurally similar propionyllysine or butyryllysine residues.acetyllysine residues.

Application:Protein/peptide immunoprecipitation for lysine acetylation proteomics; Immuno-affinity chromatography.

Scientific Description:  Lysine acetylation is an important reversible modification controlling protein activity. The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and transcription, gene silencing, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. Therefore, systematical screening of lysine acetylated substrates in various cellular pathological and physiological conditi