ENG MaxPab mouse polyclonal antibody (B01)
产品名称: ENG MaxPab mouse polyclonal antibody (B01)
英文名称: ENG MaxPab mouse polyclonal antibody (B01)
产品编号: H00002022-B01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Mouse polyclonal antibody raised against a full-length human ENG protein.
 
- Immunogen:
 - ENG (AAH14271.1, 1 a.a. ~ 658 a.a) full-length human protein.
 
- Sequence:
 - MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERDEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
 
- Host:
 - Mouse
 
- Reactivity:
 - Human
 
- Storage Buffer:
 - No additive
 
- Storage Instruction:
 - Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - Antibody reactive against mammalian transfected lysate.
 
- Note:
 - For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
 
- MSDS:
 
Download
- Applications
 
- Western Blot (Tissue lysate)
 
- ENG MaxPab polyclonal antibody. Western Blot analysis of ENG expression in human kidney.
 - Protocol Download
 
- Western Blot (Transfected lysate)
 
- Western Blot analysis of ENG expression in transfected 293T cell line (H00002022-T01) by ENG MaxPab polyclonal antibody.
Lane 1: ENG transfected lysate(72.38 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
 
- Entrez GeneID:
 - 2022
 
- GeneBank Accession#:
 - BC014271.2
 
- Protein Accession#:
 - AAH14271.1
 
- Gene Name:
 - ENG
 
- Gene Alias:
 - CD105,END,FLJ41744,HHT1,ORW,ORW1
 
- Gene Description:
 - endoglin
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
 
- Other Designations:
 - CD105 antigen,OTTHUMP00000022221,Osler-Rendu-Weber syndrome 1
 
- Related Disease
 
- Aneurysm
 - Aneurysm, Ruptured
 - Arteriovenous Malformations
 - Cardiovascular Diseases
 - Central Nervous System Vascular Malformations
 - Chromosome Aberrations
 - Diabetes Mellitus, Type 2
 - Edema
 - Epistaxis
 - Genetic Predisposition to Disease
 - Heart Defects, Congenital
 - Hypertension, Pulmonary
 - Intracranial Aneurysm
 - Intracranial Arteriovenous Malformations
 - Kidney Failure, Chronic
 - Liver Cirrhosis
 - Liver Diseases
 - Lung Neoplasms
 - Pre-Eclampsia
 
